| Win # | Season | Date | Opponent | Result | ||
|---|---|---|---|---|---|---|
| 1 | 1896 | 11/13 | H | Norman High School | W | 12-0 |
| 50 | 1908 | 10/30 | H | Arkansas | W | 27-5 |
| 100 | 1915 | 11/20 | A | Kansas State | W | 21-7 |
| 150 | 1926 | 11/6 | H | Missouri | W | 10-7 |
| 200 | 1938 | 10/29 | H | Tulsa | W | 28-6 |
| 250 | 1946 | 11/23 | H | Nebraska | W | 27-6 |
| 300 | 1952 | 10/11 | N | Texas | W | 49-20 |
| 350 | 1957 | 10/19 | H | Kansas | W | 47-0 |
| 400 | 1964 | 10/31 | A | Colorado | W | 14-11 |
| 450 | 1971 | 11/6 | A | Missouri | W | 20-3 |
| 500 | 1976 | 10/2 | A | Iowa State | W | 24-10 |
| 550 | 1981 | 10/24 | H | Oregon State | W | 42-3 |
| 600 | 1986 | 11/22 | A | Nebraska | W | 20-17 |
| 650 | 1992 | 11/7 | H | Missouri | W | 51-17 |
| 700 | 2000 | 11/25 | A | Oklahoma State | W | 12-7 |
| 750 | 2005 | 9/10 | H | Tulsa | W | 31-15 |
| 800 | 2010 | 9/4 | H | Utah State | W | 31-24 |
| 850 | 2014 | 11/22 | H | Kansas | W | 44-7 |
| 900 | 2019 | 9/28 | H | Texas Tech | W | 55-16 |
| 950 | 2024 | 11/23 | H | Alabama | W | 24-3 |